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NFKB1 — POU2F2

Pathways - manually collected, often from reviews:

• NCI Pathway Database BCR signaling pathway: NF-kappa-B/RelA complex (NFKB1-RELA) → OCT2 (POU2F2) (modification, activates) Lee et al., Proc Natl Acad Sci U S A 1999*, Bendall et al., J Biol Chem 1997*
  Evidence: assay

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• MIPS CORUM hs4 enhancer complex (faster migrating complex): hs4 enhancer complex (faster migrating complex) complex (NFKB1-POU2F1-POU2F2-RELA-YY1) Sepulveda et al., J Immunol 2004
• IRef Corum Interaction: Complex of POU2F2-POU2F1-NFKB1-YY1-RELA (association, electrophoretic mobility supershift assay) Sepulveda et al., J Immunol 2004

Text-mined interactions from Literome

Sepulveda et al., J Immunol 2004 : In addition, human hs4 enhancer activity required Oct-2 and correlated with expression of Oct coactivator from B cells (OCA-B)
Méndez et al., J Neurosci Res 2005 : Glutamate activation of Oct-2 in cultured chick Bergmann glia cells : involvement of NFkappaB
Miller et al., Mol Cell Biol 1991 : In 70Z/3 cells, transforming growth factor beta, an inhibitor of kappa-gene induction, blocks the upregulation of Oct-2 but not the activation of NF-kappa B
Lawrence et al., Infect Immun 1995 (Shock, Septic) : Diphosphoryl lipid A from Rhodobacter sphaeroides transiently activates NF-kappa B but inhibits lipopolysaccharide induction of kappa light chain and Oct-2 in the B-cell lymphoma line 70Z/3 ... RsDPLA completely repressed the long-term activation of NF-kappa B observed after 24 h of Salmonella typhosa LPS treatment and antagonized activation of oct-2 mRNA expression
Bendall et al., J Biol Chem 1997 : Transcription factor NF-kappaB regulates inducible Oct-2 gene expression in precursor B lymphocytes