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ADIPOR1 — PRKAB2
Text-mined interactions from Literome
Chen et al., J Clin Endocrinol Metab 2005
(Diabetes Mellitus, Type 2...) :
These data suggest that reduced activation of AMPK by gAD in obese and obese type 2 diabetic subjects is not caused by reduced
adiponectin receptor expression but that aspects downstream of the receptor may
inhibit AMPK signaling
Yamauchi et al., Nat Med 2007
(Diabetes Mellitus, Experimental) :
Here we show that adenovirus mediated expression of
AdipoR1 and R2 in the liver of Lepr ( -/- ) mice
increased AMP activated protein kinase (AMPK) activation and peroxisome proliferator activated receptor ( PPAR)-alpha signaling pathways, respectively
Cammisotto et al., J Mol Histol 2008
:
Adiponectin receptor
ADIPOR1 activates the intracellular second messenger
AMP activated protein kinase (AMPK) that participates in the control of the oxidative stress and apoptosis
Kim et al., Mol Endocrinol 2010
(Colonic Neoplasms) :
Adiponectin represses colon cancer cell proliferation via
AdipoR1- and -R2
mediated AMPK activation
Aouida et al., PloS one 2013
:
Further, we demonstrate
agonist-AdipoR dependent activation of protein kinase A (PKA) signaling and
AMP activated protein kinase (AMPK) phosphorylation in S. cerevisiae, which are homologous to important mammalian adiponectin-AdipoR1 signaling pathways