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Caspase-3 mediated cleavage of the NF-kappa B subunit p65 at the NH2 terminus potentiates naphthoquinone analog induced apoptosis
Mo et al., Neuroscience 2013
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In addition, the PI3K/Akt signaling pathway is activated, which inhibits caspase-3 activation and induces NF-?B p65 nuclear translocation
Pejnovic et al., Diabetes 2013
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In vitro stimulation of LGALS3 ( -/- ) peritoneal macrophages with lipopolysaccharide (LPS) and saturated fatty acid palmitate caused increased caspase-1 dependent IL-1ß production and increased phosphorylation of NF-?B p65 compared with WT cells