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ANG — VCAM1

Text-mined interactions from Literome

Kim et al., Circ Res 2001 : In the present study, we used human umbilical vascular endothelial cells ( HUVECs ) to examine the effect of Ang1 on VEGF induced expression of three adhesion molecules : intercellular adhesion molecule-1 ( ICAM-1 ), vascular cell adhesion molecule-1 ( VCAM-1 ), and E-selectin
Chae et al., Cell Physiol Biochem 2007 : Ang II induced a 40 % increase of VCAM-1 and ICAM-1 in the plasma membrane
Zhang et al., Biochem Biophys Res Commun 2013 (Atherosclerosis) : However, Ang- ( 1-7 ) significantly suppressed Ang II-induced VCAM-1 expression ... Ang- ( 1-7 ) also inhibited the Ang II-induced VCAM-1 promoter activity driven by transcription factor NF-KappaB ... The inhibitory effects of Ang- ( 1-7 ) on Ang II-induced VCAM-1 promoter activity and NF-kappaB nuclear translocation were all reversed by the competitive antagonist of Ang- ( 1-7 ) at the Mas receptor ... Our results suggest that Ang- ( 1-7 ) mediates its affects on ECs through the Mas receptor, and negatively regulates Ang II-induced VCAM-1 expression by attenuating nuclear translocation of NF-kappaB