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HMGB1 — NOX1

Text-mined interactions from Literome

Fan et al., J Immunol 2007 (Reperfusion Injury...) : Hemorrhagic shock induces NAD ( P ) H oxidase activation in neutrophils : role of HMGB1-TLR4 signaling ... Thus, PMN NAD ( P ) H oxidase activation, induced by HS/R and as mediated by HMGB1/TLR4 signaling, is an important mechanism responsible for PMN mediated inflammation and organ injury after hemorrhage
Li et al., Am J Physiol Regul Integr Comp Physiol 2009 (Acute Lung Injury...) : Furthermore, the results demonstrate that HMGB1 induces activation of NAD ( P ) H oxidase and expression of ICAM-1 in the lung, and MLVECs sequentially depend on TLR4 in the early phase and on TLR2 in the late phase following HS
Gao et al., J Neurosci 2011 (Inflammation...) : Mechanistic studies indicated that HMGB1 ( high-mobility group box 1 ), released from inflamed microglia and/or degenerating neurons, bound to microglial Mac1 ( macrophage antigen complex 1 ) and activated nuclear factor-?B pathway and NADPH oxidase to stimulate production of multiple inflammatory and neurotoxic factors