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EGFR — TCF21
Text-mined interactions from Literome
Nagel-Wolfrum et al., Mol Cancer Res 2004
(Neoplasms) :
The
transcription factor signal transducer and activator of transcription ( Stat ) 3 is
activated through the interleukin-6 family of cytokines and by binding of growth factors to the
epidermal growth factor (EGF) receptor
Tao et al., Cell Signal 2004
:
The Epstein-Barr virus ( EBV ) latent membrane protein 1 (LMP1) oncoprotein may cause multiple cellular changes including the induction of
epidermal growth factor receptor (EGFR) expression and
activation of the NFkappaB
transcription factor
Tao et al., Virus Res 2004
:
The Epstein-Barr virus ( EBV ) latent membrane protein 1 (LMP1) oncoprotein may cause multiple cellular changes, including the induction of
epidermal growth factor receptor (EGFR) expression and the
activation of the nuclear factor kappa B (NFkappaB)
transcription factor
Stehr et al., J Pediatr Surg 2006
:
In this study, we tested the role of the signal transducer and activator of transcription 1 ( STAT-1 ) as this
transcription factor is
activated by the
EGFR and known to induce p21 expression
Ziv et al., J Cell Biochem 2008
(Inflammation...) :
EGFR dependent activation
resulted in the upregulation of the
transcription factor , c-Fos, while the EGFR independent activation mode was of a shorter duration, did not affect c-Fos expression but induced IL-8 mRNA expression
Wilkinson et al., Assay Drug Dev Technol 2008
(MAP Kinase Signaling System) :
Activation of cell surface receptors, such as
epidermal growth factor receptor (EGFR) and cMET, upon ligand binding,
leads to the activation of the downstream MAPK signaling pathway and
transcription factor , activator protein 1 (AP1), which then induce the expression of genes that are important for cell growth and proliferation
RosanĂ² et al., Proc Natl Acad Sci U S A 2009
(Neoplasm Invasiveness...) :
We then demonstrate that silencing of both beta-arrestin-1 and beta-arrestin-2 inhibits ET ( A ) R-driven signaling, causing suppression of Src, mitogen activated protein kinase ( MAPK ), AKT activation, as well as
EGFR transactivation and a complete
inhibition of ET-1 induced
beta-catenin/TCF transcriptional activity and cell invasion
Miller et al., Mol Cell Biol 1998
:
The Epstein-Barr virus latent membrane protein 1 (LMP1) oncoprotein causes multiple cellular changes, including induction of
epidermal growth factor receptor (EGFR) expression and
activation of the NF-kappaB
transcription factor
Matsumoto et al., Life Sci 1998
:
Epidermal growth factor receptor mediated expression of NF-kappaB
transcription factor in osteoblastic MC3T3-E1 cells cultured under a low-calcium environment