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CDK2 — ORC3
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Findeisen et al., Eur J Biochem 1999
:
We find that chromatin binding of
ORC , Cdc6, and MCM proteins does not
require cyclin dependent kinase activities
Fernández-Cid et al., Mol Cell 2013
:
Importantly,
CDK dependent phosphorylation of
ORC inhibits OCM establishment to ensure once per cell cycle replication