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IL1A — MYLIP
Text-mined interactions from Literome
Akhtar et al., Arthritis Rheum 2010
(Osteoarthritis) :
Furthermore,
IL-1beta induced activation of signal transduction pathways associated with the expression of MMP-13
down-regulated the expression of
miR-27b
Abouheif et al., Rheumatology (Oxford) 2010
(Arthritis, Experimental) :
The expression of
miR-34a was significantly
up-regulated by
IL-1ß
Jones et al., Arterioscler Thromb Vasc Biol 2012
(Inflammation) :
In human lymphatic endothelial cells,
miR-1236 is upregulated in
response to
IL-1ß , a negative regulator of VEGFR-3
Motsch et al., PloS one 2012
(Epstein-Barr Virus Infections...) :
We show that the proinflammatory cytokine
interleukin 1 alpha (IL1A) is a
target for
miR-142-3p and the oncogenic BCL6 for miR-205
Haneklaus et al., J Immunol 2012
:
However, overexpression of
miR-223 prevents accumulation of NLRP3 protein and
inhibits IL-1ß production from the inflammasome
Iyer et al., PloS one 2012
(Brain Diseases...) :
qPCR and western blot were used to evaluate the
effects of overexpression or knockdown of
miR-146a on
IL-1ß signaling
Xu et al., J Immunol 2013
(Psoriasis) :
Specific inhibition of
miR-31 suppressed NF-?B-driven promoter luciferase activity and the basal and TNF-a induced production of
IL-1ß , CXCL1/growth related oncogene-a, CXCL5/epithelial derived neutrophil activating peptide 78, and CXCL8/IL-8 in human primary keratinocytes
Shi et al., Glia 2013
(Inflammation...) :
The overexpression of
miR-195 contributed to lipopolysaccharide induced expression of proinflammatory cytokines
IL-1ß , TNF-a, and iNOS in cultured microglia
Xie et al., PloS one 2013
(Inflammation) :
These results indicate that
miR-181a regulates inflammatory responses by directly targeting the 3'-UTR of IL1a and down regulating
IL1a levels ... Thus, we provide the first evidence for anti-inflammatory effects of
miR-181a mediated at least in part by down regulating
IL1a
Kutty et al., Molecular vision 2013
:
The
miR-146a induction was more
dependent on
IL-1ß , since its omission from the cytokine mix resulted in a greatly reduced response ... Our results clearly show that both miR-146a and
miR-146b-5p are expressed in human RPE cells in culture and their expression is highly
induced by proinflammatory cytokines ( IFN-? + TNF-a +
IL-1ß )
Park et al., Osteoarthritis Cartilage 2013
(Osteoarthritis, Knee) :
Stimulation with
IL-1ß led to a significant reduction in
miR-558 expression in normal and OA chondrocytes
Lippai et al., PloS one 2013
(Alcoholism...) :
Alcohol induced
miR-155 regulates TNFa and MCP1 expression but not caspase dependent
IL-1ß increase in neuroinflammation