Gene interactions and pathways from curated databases and text-mining

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IL1A — MYLIP

Text-mined interactions from Literome

Akhtar et al., Arthritis Rheum 2010 (Osteoarthritis) : Furthermore, IL-1beta induced activation of signal transduction pathways associated with the expression of MMP-13 down-regulated the expression of miR-27b
Abouheif et al., Rheumatology (Oxford) 2010 (Arthritis, Experimental) : The expression of miR-34a was significantly up-regulated by IL-1ß
Jones et al., Arterioscler Thromb Vasc Biol 2012 (Inflammation) : In human lymphatic endothelial cells, miR-1236 is upregulated in response to IL-1ß , a negative regulator of VEGFR-3
Motsch et al., PloS one 2012 (Epstein-Barr Virus Infections...) : We show that the proinflammatory cytokine interleukin 1 alpha (IL1A) is a target for miR-142-3p and the oncogenic BCL6 for miR-205
Haneklaus et al., J Immunol 2012 : However, overexpression of miR-223 prevents accumulation of NLRP3 protein and inhibits IL-1ß production from the inflammasome
Iyer et al., PloS one 2012 (Brain Diseases...) : qPCR and western blot were used to evaluate the effects of overexpression or knockdown of miR-146a on IL-1ß signaling
Xu et al., J Immunol 2013 (Psoriasis) : Specific inhibition of miR-31 suppressed NF-?B-driven promoter luciferase activity and the basal and TNF-a induced production of IL-1ß , CXCL1/growth related oncogene-a, CXCL5/epithelial derived neutrophil activating peptide 78, and CXCL8/IL-8 in human primary keratinocytes
Shi et al., Glia 2013 (Inflammation...) : The overexpression of miR-195 contributed to lipopolysaccharide induced expression of proinflammatory cytokines IL-1ß , TNF-a, and iNOS in cultured microglia
Xie et al., PloS one 2013 (Inflammation) : These results indicate that miR-181a regulates inflammatory responses by directly targeting the 3'-UTR of IL1a and down regulating IL1a levels ... Thus, we provide the first evidence for anti-inflammatory effects of miR-181a mediated at least in part by down regulating IL1a
Kutty et al., Molecular vision 2013 : The miR-146a induction was more dependent on IL-1ß , since its omission from the cytokine mix resulted in a greatly reduced response ... Our results clearly show that both miR-146a and miR-146b-5p are expressed in human RPE cells in culture and their expression is highly induced by proinflammatory cytokines ( IFN-? + TNF-a + IL-1ß )
Park et al., Osteoarthritis Cartilage 2013 (Osteoarthritis, Knee) : Stimulation with IL-1ß led to a significant reduction in miR-558 expression in normal and OA chondrocytes
Lippai et al., PloS one 2013 (Alcoholism...) : Alcohol induced miR-155 regulates TNFa and MCP1 expression but not caspase dependent IL-1ß increase in neuroinflammation