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IL6 — TAB1
Text-mined interactions from Literome
Frobøse et al., Mol Endocrinol 2006
:
Suppressor of cytokine Signaling-3
inhibits interleukin-1 signaling by targeting the
TRAF-6/TAK1 complex
Thiefes et al., EMBO Rep 2006
:
YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and
interleukin-1-inducible activation of endogenous TAK1,
TAB1 and TAB2 ... YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and
interleukin-1-inducible activation of endogenous TAK1,
TAB1 and TAB2 ... YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and
interleukin-1-inducible activation of endogenous
TAK1 , TAB1 and TAB2
Kim et al., PloS one 2009
(Colitis) :
Finally, we showed that
TAK1 is
essential for
interleukin 1- and bacterial components induced expression of cytoprotective factors such as interleukin 6 and cycloxygenase 2
Hamidi et al., J Biol Chem 2012
(Inflammation) :
Expression of a K34R-mutant
TAK1 led to a reduced NF-?B activation,
IL-6 promoter activity, and proinflammatory cytokine secretion by TNF-a stimulated PC-3U cells
Arcipowski et al., PloS one 2012
:
We determined that
TAK1 was
required for JNK activation and
interleukin-6 (IL-6) production mediated by CD40 and LMP1, in both mouse and human B cells