Gene interactions and pathways from curated databases and text-mining

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IL6 — TAB1

Text-mined interactions from Literome

Frobøse et al., Mol Endocrinol 2006 : Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex
Thiefes et al., EMBO Rep 2006 : YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and interleukin-1-inducible activation of endogenous TAK1, TAB1 and TAB2 ... YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and interleukin-1-inducible activation of endogenous TAK1, TAB1 and TAB2 ... YopP, but not the catalytically inactive mutant YopP ( C172A ), also suppresses basal and interleukin-1-inducible activation of endogenous TAK1 , TAB1 and TAB2
Kim et al., PloS one 2009 (Colitis) : Finally, we showed that TAK1 is essential for interleukin 1- and bacterial components induced expression of cytoprotective factors such as interleukin 6 and cycloxygenase 2
Hamidi et al., J Biol Chem 2012 (Inflammation) : Expression of a K34R-mutant TAK1 led to a reduced NF-?B activation, IL-6 promoter activity, and proinflammatory cytokine secretion by TNF-a stimulated PC-3U cells
Arcipowski et al., PloS one 2012 : We determined that TAK1 was required for JNK activation and interleukin-6 (IL-6) production mediated by CD40 and LMP1, in both mouse and human B cells