Gene interactions and pathways from curated databases and text-mining

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RHO — SRC

Text-mined interactions from Literome

Fincham et al., J Cell Sci 1999 (Cell Transformation, Neoplastic) : Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation
Hunt et al., J Am Soc Nephrol 2005 (Calcium Signaling) : Screening with modulators of specific signaling pathways identified reversible increases in flux with Src tyrosine and Rho kinase inhibition
Vulin et al., Endocrinology 2005 : Src increased prolactin gene transcription was inhibited by expression of a blocking Rho-mutant ( RhoN19 ), suggesting that Src acted through or required active Rho
Samarakoon et al., J Mol Cell Cardiol 2008 : Thus, two distinct pathways involving the EGFR/pp60(c-src)/MEK-ERK pathway and Rho/ROCK dependent SMAD2 activation are required for TGF-beta1 induced PAI-1 expression in VSMC
Granot-Attas et al., Mol Biol Cell 2009 : Increasing Src activity or inhibiting Rho or its downstream effector Rho kinase in EKO osteoclasts rescues their podosomal stability phenotype, indicating that cyt-PTPe affects podosome stability by functioning upstream of these molecules
Tripathi et al., Mol Cell Biol 2009 : Next, we examined the effect of Cdk5 activity on Src , a known regulator of Rho
Arpaia et al., Oncogene 2012 (Neoplasm Metastasis...) : Rho-GTPases are important regulators of p130 ( Cas ), which is crucial for both normal cell migration and Src kinase mediated metastasis of cancer cells
Basavarajappa et al., Mol Cell Biol 2011 : We also found that rhodopsin regulated Src kinase activation in retina leads to the phosphorylation of Grb14