Gene interactions and pathways from curated databases and text-mining

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IL4 — RAG1

Text-mined interactions from Literome

Kajiwara et al., Cell Immunol 2004 : We examined the expression of recombination activating genes ( RAG-1 and RAG-2 ) and activation induced cytidine deaminase ( AID ) by mature human blood B cells stimulated with anti-CD40 in the presence of IL-4 or IL-13 ... In addition, IL-4 dependent RAG expression combined with AID and IgE expression allowed predominant expression of newly rearranged lambda light chains on IgE+ cells generated from kappa+ cells
Tagoh et al., Blood 1996 : Among recombinant cytokines, interleukin-3 (IL-3), IL-6, and IL-7, but not IL-2, IL-4, stem cell factor (SCF), and granulocyte-macrophage colony stimulating factor ( GM-CSF ) could induce RAG-1 activation in FL8.2.4.4 cells, and a significant synergistic effect between IL-3, IL-6, and IL-7 was observed
Muraguchi et al., Leukemia & lymphoma 1998 : Among the cytokines, IL-3, IL-6, and IL-7, but not IL-2, IL-4 , SCF, GM-CSF induces RAG activation