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IL4 — RAG1
Text-mined interactions from Literome
Kajiwara et al., Cell Immunol 2004
:
We examined the expression of recombination activating genes (
RAG-1 and RAG-2 ) and activation induced cytidine deaminase ( AID ) by mature human blood B cells stimulated with anti-CD40 in the
presence of
IL-4 or IL-13 ... In addition,
IL-4 dependent
RAG expression combined with AID and IgE expression allowed predominant expression of newly rearranged lambda light chains on IgE+ cells generated from kappa+ cells
Tagoh et al., Blood 1996
:
Among recombinant cytokines,
interleukin-3 (IL-3), IL-6, and IL-7, but not IL-2, IL-4, stem cell factor (SCF), and granulocyte-macrophage colony stimulating factor ( GM-CSF ) could
induce RAG-1 activation in FL8.2.4.4 cells, and a significant synergistic effect between IL-3, IL-6, and IL-7 was observed
Muraguchi et al., Leukemia & lymphoma 1998
:
Among the cytokines, IL-3, IL-6, and IL-7, but not IL-2,
IL-4 , SCF, GM-CSF
induces RAG activation