◀ Back to TNF
BAD — TNF
Text-mined interactions from Literome
Pastorino et al., J Biol Chem 1999
:
Tumor necrosis factor induces phosphorylation and translocation of
BAD through a phosphatidylinositide-3-OH kinase dependent pathway ...
Tumor necrosis factor (TNF) induced the phosphorylation of
BAD at serine 136 in HeLa cells under conditions that are not cytotoxic
Finkel-Jimenez et al., J Immunol 2002
:
BAD1 , an essential virulence factor of Blastomyces dermatitidis,
suppresses host
TNF-alpha production through TGF-beta dependent and -independent mechanisms ... However, in contrast to yeast cell surface BAD1, which induced TGF-beta, soluble BAD1 failed to do so and
TNF-alpha suppression
mediated by soluble
BAD1 was unaffected by neutralization of TGF-beta ... Thus,
BAD1 of B. dermatitidis
induces suppression of
TNF-alpha and progressive infection by both TGF-beta dependent and -independent mechanisms
Pastorino et al., Am J Physiol Gastrointest Liver Physiol 2003
:
Additionally, ethanol exposed cells display a blunting of
TNF-alpha induced Akt activation and
Bcl-2 antagonist of cell death phosphorylation that may account, in part, for the increased sensitivity of the mitochondria to Bax mediated damage
Tian et al., Zhongguo Zhong Yao Za Zhi 2010
(Arthritis, Rheumatoid) :
Res inhibited
TNF-alpha induced phosphorylation of Akt and
BAD in RA FLS