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IL10 — PTGES

Text-mined interactions from Literome

Degousee et al., J Biol Chem 2006 (Inflammation) : In neonatal cardiomyocytes, interleukin-1beta and lipopolysaccharide (LPS) both stimulated mPGES-1 mRNA expression and increased mPGES-1 mRNA stability and protein synthesis but failed to increase mPGES-1 mRNA transcription
Mosca et al., J Leukoc Biol 2007 : Alternatively activated M2 monocytes-macrophages exposed to IL-4, IL-13, or IL-10 did not express mPGES-1, whereas in these cells, IL-4, IL-13, and to a lesser extent, IL-10 or IFN-gamma inhibited LPS induced, mPGES-1 expression
Cho et al., Mol Immunol 2011 : Protein expression of mPGES-1 , a downstream enzyme of COX-2, was also markedly diminished by IL-4 but not by IL-10 , maximizing the inhibitory activity