Gene interactions and pathways from curated databases and text-mining

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FAS — STAT1

Text-mined interactions from Literome

Stephanou et al., J Biol Chem 2001 (Reperfusion Injury) : Moreover, STAT-1 is critical for the induction of Fas receptor and Fas ligand expression by ischemia/reperfusion ( I/R ) ... These results indicate that Fas/FasL genes and apoptosis are activated by STAT-1 in cardiac myocytes exposed to I/R and these effects are dependent on the Ser-727 but not the Tyr-701 phosphorylation sites of STAT-1
Le Clorennec et al., Blood 2006 (Cell Transformation, Viral...) : Epstein-Barr virus ( EBV ) induces CD95 expression and the CD95 gene ( FAS ) is regulated by NF-kappaB, STAT1 , and/or p53