Gene interactions and pathways from curated databases and text-mining

◀ Back to FGF2

FGF2 — KLK3

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: KLK3 → FGF2 (decreases)
    Evidence: bFGF diminished prostate-specific antigen protein in the supernatants of androgen-stimulated human prostate cancer cells LNCaP by 80%.

Text-mined interactions from Literome

DuliƄska et al., Acta biochimica Polonica 2002 (Prostatic Hyperplasia) : DHT, E, bFGF , EGF or both DHT + bFGF and DHT + EGF increased PAP and PSA mRNA levels in a time- and dose dependent manner
Udayakumar et al., Mol Carcinog 2003 (Carcinoma...) : Pharmacological inhibition of FGF receptor signaling inhibits LNCaP prostate tumor growth, promatrilysin, and PSA expression