Gene interactions and pathways from curated databases and text-mining

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CD8A — IL1B

Text-mined interactions from Literome

Andrade et al., J Acquir Immune Defic Syndr 2010 (Acquired Immunodeficiency Syndrome) : CD8 ( + ) T lymphocytes depletion reduced IL-1beta and TNF-alpha release in the older groups, however, it did not significantly alter their IFN-gamma production
Wang et al., Exp Cell Res 2010 : Moreover, the inflammatory cytokine IL-1beta , either exogenously added or produced by CD14 ( + ) monocytes in culture, could trigger expression of high levels of PGE ( 2 ) by hUC-MSCs, whereas inclusion of the IL-1 receptor antagonist (IL-1RA) in the culture down-regulated not only PGE ( 2 ) expression, but also reversed the promotional effect of CD14 ( + ) monocytes and partially restored CD4 ( + ) and CD8 ( + ) T cell proliferation and IFN-gamma secretion
Martín et al., Hepatology 1994 (Chronic Disease...) : To assess changes in immune function during therapy of chronic hepatitis B patients, spontaneous and mitogen induced production of tumor necrosis factor-alpha, interleukin-1 beta, interleukin-6, interferon-alpha and interferon-gamma were measured-along with serum levels of soluble CD4, soluble CD8 , soluble interleukin-2 receptor and beta 2-microglobulin-before, during and after a 6-wk course of granulocyte-macrophage colony stimulating factor in nine patients with chronic hepatitis B. Treatment statistically enhanced spontaneous production of tumor necrosis factor-alpha ( p < 0.05 ) and interleukin-1 beta ( p < 0.02 )