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EPHB2 — MYD88
Text-mined interactions from Literome
Dubourdeau et al., J Immunol 2006
(MAP Kinase Signaling System) :
Our investigations revealed that immunocompetent TLR2, TLR4, and
MyD88 knockout mice were not more susceptible to invasive aspergillosis as compared with wild-type mice and that the in vitro phosphorylation of the MAPKs
ERK and p38 was not
affected in TLR2, TLR4, or MyD88 knockout mice following stimulation with conidia
Slack et al., Eur J Immunol 2007
:
Conversely,
ERK activation in response to the TLR2 agonist Pam3Cys is completely
MyD88 dependent and unaffected by Syk deficiency
Lee et al., Nat Med 2010
(Intestinal Neoplasms...) :
MyD88 ( myeloid differentiation primary response gene 88 ) -independent activation of ERK by epidermal growth factor (EGF)
increased p-ERK and c-Myc and restored the multiple intestinal neoplasia ( Min ) phenotype in Apc ( min/+ ) /Myd88 ( -/- ) mice
Oliveira et al., Infect Immun 2011
(Brucellosis...) :
Extracellular signal regulated kinase 1 ( ERK1 ) and
ERK2 and p38 as well as p65 NF-?B phosphorylation was profoundly
impaired in IRAK-4 ( -/- ) and
MyD88 ( -/- ) macrophages activated by Brucella
Watts et al., Am J Physiol Cell Physiol 2011
(MAP Kinase Signaling System...) :
Basolateral LPS inhibits NHE3 and HCOFormula absorption through
TLR4/MyD88 dependent
ERK activation in medullary thick ascending limb
Good et al., J Biol Chem 2012
(MAP Kinase Signaling System) :
These results indicate that the effect of basolateral LPS to inhibit HCO ( 3 ) ( - ) absorption in the MTAL through
MyD88 dependent
ERK activation depends on a novel interaction between TLR4 and TLR2
Wu et al., Food Chem Toxicol 2012
(Melanoma) :
Our flow cytometry and Western blot data showed that paclitaxel activated
TLR4-MyD88-ERK signaling and that IS treatment could effectively
inhibit this paclitaxel induced activation of
TLR4-MyD88-ERK signaling
Ryu et al., Cancer prevention research (Philadelphia, Pa.) 2013
(Cell Transformation, Neoplastic...) :
Inhibition of Snail and
MyD88 reversed suppression of 15-PGDH expression, and siMyD88
reduced phosphorylated
ERK1/2