Gene interactions and pathways from curated databases and text-mining

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CREB3 — NR4A1

Text-mined interactions from Literome

Darragh et al., Biochem J 2005 (MAP Kinase Signaling System) : The induction of Nur77 was also blocked by A-CREB , suggesting that MSKs control Nur77 transcription by phosphorylating CREB bound to the two AP-1-like elements
Inaoka et al., Mol Reprod Dev 2008 (Leydig Cell Tumor) : The rapid induction of NGFI-B/Nur77 gene expression by LH/hCG in MA-10 cells appears to be mediated by both CREB and Jun family proteins through the cAMP-protein kinase A (PKA) pathway
Lam et al., J Neurochem 2010 : CREB dependent Nur77 induction following depolarization in PC12 cells and neurons is modulated by MEF2 transcription factors ... We show that while CREB is necessary for Ca2+ activated Nur77 expression MEF2 functions to modulate CREB dependent Nur77 expression by acting as a repressor in quiescent cells
Hawk et al., J Clin Invest 2012 (Memory Disorders) : These CREB regulated Nr4a genes encode ligand independent `` orphan '' nuclear receptors