Gene interactions and pathways from curated databases and text-mining

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EIF2S1 — IGF1

Text-mined interactions from Literome

Li et al., Endocrinology 2003 (Body Weight...) : PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver
Eley et al., Mol Cell Biochem 2008 : Both insulin ( 1 nM ) and insulin-like growth factor I (IGF-I) ( 13.2 nM ) attenuated the depression of protein synthesis by PIF and the increased phosphorylation of eIF2alpha , by inhibiting the activation ( autophosphorylation ) of the dsRNA dependent protein kinase ( PKR ) by induction of protein phosphatase 1