Gene interactions and pathways from curated databases and text-mining

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CXCL1 — PARP1

Text-mined interactions from Literome

Kanemitsu et al., Blood 2005 : In vitro, CXCL13 activated the small guanosine triphosphatase ( GTPase ) Rap1 in B cells, and corroborating this observation, a deficiency of RAPL, the Rap1 effector molecule, caused a significant reduction in shear-resistant B-cell adhesion to intercellular adhesion molecule 1 ( ICAM-1 )
Amiri et al., Oncogene 2006 (Melanoma) : However, activation of the PARP-1 enzymatic activity enhances CXCL1 expression, owing to the loss of PARP-1 binding to the CXCL1 promoter, accompanied by enhanced binding of p65 to the promoter