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EPHB2 — MKNK1
Text-mined interactions from Literome
Ishida et al., Circ Res 2003
:
PD98059 or introduction of kinase-inactive MEK1/MKK1, but not SB202190 or kinase-inactive p38 MAP kinase, inhibited Ang II-induced Mnk1 activation and eIF4E phosphorylation, suggesting that
ERK , but not p38 MAP kinase, is
required for Ang II-induced
Mnk1-eIF4E activation
Banko et al., J Neurochem 2004
:
NMDA receptor activation results in PKA- and
ERK dependent
Mnk1 activation and increased eIF4E phosphorylation in hippocampal area CA1 ... The NMDA induced activation of
Mnk1 and increased phosphorylation of eIF4E were
dependent on PKA and
ERK , but not PKC, and were present in synaptoneurosome preparations ... Immunohistochemical analysis revealed that the PKA- and
ERK dependent increases in
Mnk1 activation induced by NMDA also occurred in dendrites
Mariappan et al., J Biol Chem 2005
:
VEGF induced phosphorylation of
Mnk1 and eIF4E
required phosphorylation of PLCgamma, c-Src, and
Erk ... VEGF also stimulates
Erk dependent phosphorylation of
Mnk1 and eIF4E, crucial events in the initiation phase of protein translation