Gene interactions and pathways from curated databases and text-mining

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RAC1 — STK16

Text-mined interactions from Literome

Aoukaty et al., J Immunol 2005 (Lymphoproliferative Disorders...) : Ligation of 2B4 resulted in the phosphorylation of the guanine nucleotide exchange factor, Vav-1, and subsequent activation of the GTP binding protein Rac-1 ( but not Ras ) and the serine-threonine kinase Raf-1 in healthy but not XLP derived NK cells
Bourguignon et al., J Neurochem 2007 : To determine the cellular and molecular basis of these events, we focused on PKN gamma, a Rac1 activated serine/threonine kinase in astrocytes
Westwick et al., Mol Cell Biol 1997 (Cell Transformation, Neoplastic) : Rac1 is distinct from RhoA in its ability to bind and activate the p65 PAK serine/threonine kinase , to induce lamellipodia and membrane ruffling, and to activate the c-Jun NH2-terminal kinase (JNK)
Yablonski et al., EMBO J 1998 : This serine/threonine kinase is activated by GTP bound Rac1 or Cdc42