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IRF6 — TPO
Text-mined interactions from Literome
Zhang et al., J Interferon Cytokine Res 2010
(Inflammation) :
LPS inhibited
Tpo gene expression in astrocytes and microglia, but not in neurons, most likely due to absence of Toll-like receptor 4 in neurons ... In these cells,
LPS significantly
up-regulated Tpo mRNA expression
Nazar et al., Endocrinology 2012
:
Moreover,
LPS increased TSH stimulated
TPO promoter activity ... Additionally, our results indicate that p65 phosphorylation of serine 536 constitutes an essential step in the p65
dependent ,
LPS induced transcriptional expression of
TPO