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IL2 — MTX1

Text-mined interactions from Literome

Hobl et al., Clin Exp Rheumatol 2011 (Arthritis, Rheumatoid) : MTX reduces the production of pro-inflammatory cytokines such as interleukin (IL)-1, IL-2 , IL-6 and interferon (INF)-?, while the gene expression of anti-inflammatory Th2 cytokines like IL-4 and IL-10 is increased - altogether resulting in the anti-inflammatory effect
Segal et al., Arthritis Rheum 1989 : In a 2-step assay using LBRM-33-1A5 ( 1A5 ) and CTLD cells, MTX inhibited the secretion of IL-2 by 1A5 lymphoma cells in response to phytohemagglutinin and IL-1
Crilly et al., J Rheumatol 1995 (Arthritis, Rheumatoid) : To investigate the effect of oral methotrexate (MTX) on circulating levels of interleukin 6 (IL-6) and soluble IL-2 receptor ( sIL-2R ) in patients with rheumatoid arthritis ( RA )
Meyer et al., J Rheumatol 1993 (Arthritis, Rheumatoid) : MTX had no effect on interleukin 1 stimulated production of prostaglandin E, hyaluronic acid and collagenase