◀ Back to CXCL12

CXCL12 — JAK3

Text-mined interactions from Literome

Moriguchi et al., J Biol Chem 2005 : CXCL12 signaling is independent of Jak2 and Jak3 ... We found that the lack of Jak3 had no effect on CXCL12 signaling or chemotaxis nor did overexpression of wild-type versions of the kinase
Lee et al., Int J Biochem Cell Biol 2007 (MAP Kinase Signaling System) : The OSM stimulated expression of SDF-1 in hATSCs was completely abrogated by pretreatment of the cells with U0126, an MEK-specific inhibitor, but not with AG490, a JAK2 inhibitor, or WHI-P131, a JAK3 inhibitor, suggesting that ERK, but not JAK2 and JAK3 , is involved in the OSM induced expression of SDF-1