Gene interactions and pathways from curated databases and text-mining

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MAP3K8 — PTGS2

Text-mined interactions from Literome

Eliopoulos et al., EMBO J 2002 (Inflammation) : Induction of COX-2 by LPS in macrophages is regulated by Tpl2 dependent CREB activation signals
Lee et al., Cancer Res 2009 : Our results show that Tpl2 plays a key role in arsenite induced COX-2 expression and PGE ( 2 ) production and further elucidate the role of Tpl2 in arsenite signals that activate ERK/JNK and NF-kappaB/AP-1 in JB6 P+ cells