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AKT2 — BPNT1
Text-mined interactions from Literome
Ge et al., Oncogene 2000
(Multiple Myeloma) :
In myeloma cells,
PIP 's are
required for phosphorylation of
Akt , a key event leading to inhibition of apoptosis
Kwon et al., BMB Rep 2010
:
However, treatment with phosphatases PTEN or SHIP abrogates the association between Akt and B23, indicating that nuclear
PIP ( 3 )
regulates the
Akt/B23 interaction by controlling the concentration and subcellular dynamics of these two proteins
Mun et al., Mol Cells 2012
:
Examination of the localization of a PH-domain containing PIP3 reporter, PhdA-GFP, and the activation of Akt/Pkb and other Ras proteins in Rap1CA cells reveals that activated Rap1 has no effect on the production of
PIP3 or the
activation of
Akt/Pkb and Ras proteins in response to chemoattractant stimulation