Gene interactions and pathways from curated databases and text-mining

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AKT2 — BPNT1

Text-mined interactions from Literome

Ge et al., Oncogene 2000 (Multiple Myeloma) : In myeloma cells, PIP 's are required for phosphorylation of Akt , a key event leading to inhibition of apoptosis
Kwon et al., BMB Rep 2010 : However, treatment with phosphatases PTEN or SHIP abrogates the association between Akt and B23, indicating that nuclear PIP ( 3 ) regulates the Akt/B23 interaction by controlling the concentration and subcellular dynamics of these two proteins
Mun et al., Mol Cells 2012 : Examination of the localization of a PH-domain containing PIP3 reporter, PhdA-GFP, and the activation of Akt/Pkb and other Ras proteins in Rap1CA cells reveals that activated Rap1 has no effect on the production of PIP3 or the activation of Akt/Pkb and Ras proteins in response to chemoattractant stimulation