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AKT2 — CSK
Text-mined interactions from Literome
Dey et al., Exp Cell Res 2005
:
CSK negatively regulates nerve growth factor induced neural differentiation and
augments AKT kinase activity ... These data suggest a distinct
requirement for
CSK in the regulation of NGF/TrkA activation of RAS, RAC, ERK, and
AKT via the differential control of SFKs in the orchestration of neuronal differentiation
Chaurasia et al., Mol Cell Biol 2010
(Sepsis) :
Furthermore, primary macrophages derived from PDK-1 ( Deltamyel ) mice lack LPS- and
Pam3CSK4 stimulated
AKT activity but exhibit increased mRNA expression and release of tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6)