Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
FOXO4
→
Complex of FOXO4-YWHAQ
(decreases, FOXO4/YWHAQ Activity)
Evidence: in the case of FoxO4, the binding to the chaperone protein 14-3-3 is necessary for the complete inhibition of DNA binding (Obsil et al., 2003).
NCI Pathway Database FoxO family signaling:
FOXO4 (FOXO4)
→
FOXO4/14-3-3 family complex (FOXO4-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB)
(translocation, collaborate)
Brownawell et al., Mol Cell Biol 2001 Evidence: mutant phenotype, physical interaction
NCI Pathway Database FoxO family signaling:
Ran/GTP/Exportin 1 complex (RAN-XPO1)
→
FOXO4/14-3-3 family complex (FOXO4-YWHAH_YWHAZ_YWHAQ_SFN_YWHAE_YWHAG_YWHAB)
(translocation, activates)
Brownawell et al., Mol Cell Biol 2001 Evidence: mutant phenotype, physical interaction