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CDX2 — FGF4

Text-mined interactions from Literome

Keenan et al., Dev Biol 2006 (MAP Kinase Signaling System) : FGF signal transduction and the regulation of Cdx gene expression ... We show that FGF and wnt signaling can interact in the regulation of Cdx genes and during gastrula stages the normal expression of the Cdx genes requires the activity of both pathways
Shimosato et al., BMC developmental biology 2007 : TS cells can be established from ES cells by the artificial repression of Oct3/4 or the upregulation of Cdx2 in the presence of FGF4 on feeder cells
Murohashi et al., Stem Cells 2010 : We provide evidence that FRS2alpha mediates activation of the extracellular signal regulated progein kinase ( ERK ) pathway to enhance expression of transcription factor Cdx2 in TS cells in response to FGF4