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AGRP — NPY
Text-mined interactions from Literome
Qian et al., Mol Cell Biol 2002
:
As AgRP and the orexigenic peptide NPY are coexpressed in neurons of the arcuate nucleus, we generated AgRP and NPY double-knockout ( Agrp ( -/- ) ; Npy ( -/- ) ) mice to determine whether
NPY or AgRP
plays a compensatory role in
Agrp ( -/- ) or NPY-deficient ( Npy ( -/- ) ) mice, respectively
Bugarith et al., Endocrinology 2005
(Body Weight) :
We found that
NPY-SAP profoundly
reduced NPY Y1 receptor and alpha MSH immunoreactivity, as well as NPY,
Agouti gene related protein (AGRP) , and cocaine and amphetamine related transcript mRNA expression in the BMH
Volkoff et al., Gen Comp Endocrinol 2005
:
In goldfish, nutritional status can modify the expression of mRNAs encoding a number of these peptides, which provides further evidence for their roles as appetite regulators : ( 1 ) brain mRNA expression of CCK, CART, tachykinins, galanin, ghrelin, and
NPY undergo peri-prandial variations ; and ( 2 ) fasting
increases the brain mRNA expression of NPY,
AgRP , and ghrelin as well as serum ghrelin levels, and decreases the brain mRNA expression of tachykinins, CART, and CCK