Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Webb et al., J Recept Signal Transduct Res 2010 : Inhibition of p42/p44(mapk) or src kinases prevented the increase in PGI ( 2 ) and cAMP observed in response to BK or IGF-1, indicating a role for these kinases in the regulation of cPLA(2) activity in the VSMC
Patel et al., Biochem J 1996 : These results provide direct evidence for the involvement of p42 and p44 MAPK in the PGI2 response of intact endothelial cells : we have shown that both the endothelial P2Y purinoceptors are linked to activation of MAPK, and that activation of this pathway is a requirement for the stimulation by ATP/ADP of endothelial PGI2 production