Grösch et al., Biochem Biophys Res Commun 1999
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Here we demonstrate that mutational inactivation of a CREB binding site ( CRE ) present within the promoter completely abolished APE promoter activation by H ( 2 ) O ( 2 ), indicating that CREB is required for APE induction
Yang et al., J Biol Chem 2010
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Selective depletion of CREB using RNA interference prevented glutamate induced up-regulation of APE1