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CD44 — ITGB1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: ITGB1 — CD44 (colocalization, imaging technique) Su et al., EMBO J 2011*
• IRef Intact Interaction: Complex of 102 proteins (association, pull down) Tang et al., Proteomics 2010
• IRef Intact Interaction: Complex of 156 proteins (association, anti tag coimmunoprecipitation) Lau et al., Cell 2012

Text-mined interactions from Literome

Wang et al., Exp Cell Res 2005 (Breast Neoplasms) : Using flow cytometric analysis and immunofluorescence staining, we demonstrated that cross linking of CD44 resulted in a marked induction of the expression of lymphocyte function associated antigen-1 ( LFA-1 ) and very late antigen-4 (VLA-4) by exocytosis ... This shows that CD44 cross linking induces LFA-1 and VLA-4 expression in MDA-MB-435S cells and increases integrin mediated adhesion to endothelial cells, resulting in the transendothelial migration of breast cancer cells
Sackstein et al., Curr Opin Hematol 2011 : Engagement of CD44 or of HCELL directly induces VLA-4 activation via G-protein dependent signaling, triggering a ` step 2-bypass pathway ' of cell migration, and extravascular lodgment, in absence of chemokine receptor engagement