Gene interactions and pathways from curated databases and text-mining

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PPARA — SCARB1

Text-mined interactions from Literome

Chinetti et al., Circulation 2000 (Arteriosclerosis) : Activation of PPARalpha and PPARgamma resulted in the induction of CLA-1 protein expression in monocytes and in differentiated macrophages
Malerød et al., Biochem Biophys Res Commun 2003 : In contrast, PPARalpha increased SR-BI levels only in hepatocytes and liver endothelial cells
Lopez et al., Mol Cell Endocrinol 2006 : Activation of the rat scavenger receptor class B type I gene by PPARalpha ... The present study examines the effects of PPARalpha on SR-BI expression ... PPARalpha/RXR increased the activity of the SR-BI promoter, an effect that was enhanced by clofibrate ... In addition, mutational analysis studies confirmed that this PPRE motif is responsible for the PPARalpha/RXRalpha dependent activation of the rat SR-BI promoter in the cell lines examined