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Lokuta et al., Proc Natl Acad Sci U S A 2003
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Further, both calpain inhibition and stimulation with IL-8 and formyl-Met-Leu-Phe ( fMLP ) induced an increase in Cdc42 and Rac activation
Coward et al., Clin Exp Allergy 2004
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The NF-kappaB inhibitors, calpain inhibitor 1 ( 10 microm ), pentoxifylline ( 0.5 mm ), pyrrolidine dithiocarbamate ( PDTC, 10 microm ) or gliotoxin ( 1 pg/mL ) reduced the generation of GM-CSF, TNF-alpha and IL-8 in parallel with their inhibition of NF-kappaB