◀ Back to NFKB1
NFKB1 — RABEPK
Text-mined interactions from Literome
Cowdery et al., J Immunol 1999
:
Although LPS alone is a poor inducer of
p40 transcription, both LPS and CpG DNA
induce similar nuclear translocation of
NF-kappaB
Zhang et al., Cell Immunol 2000
:
NF-kappa B regulates the LPS induced expression of interleukin 12
p40 in murine peritoneal macrophages : roles of PKC, PKA, ERK, p38 MAPK, and proteasome
Pahan et al., J Biol Chem 2001
:
Induction of the DNA binding as well as the transcriptional activity of NF-kappaB by p40 ( 2 ) and inhibition of p40 ( 2 ) -induced expression of iNOS by SN50, a cell-permeable peptide carrying the nuclear localization sequence of p50 NF-kappaB, but not by SN50M, a nonfunctional peptide mutant, suggests that
p40 ( 2 )
induces the expression of iNOS through the activation of
NF-kappaB
Maruyama et al., J Immunol 2003
:
The induction of the IL-12
p40 gene is
regulated by
NF-kappaB in the presence of IFN-gamma
Jana et al., J Neurochem 2003
:
Activation of
NF-kappaB as well as C/EBPbeta by p40 and inhibition of
p40 induced expression of TNF-alpha by Deltap65, a dominant negative mutant of p65, and DeltaC/EBPbeta, a dominant negative mutant of C/EBPbeta, suggests that p40 induces the expression of TNF-alpha through the activation of NF-kappaB and C/EBPbeta
Hoentjen et al., Blood 2005
:
In this study, we investigated the
role of
nuclear factor-kappa B (NF-kappaB) and signal transducers and activators of transcription 3 ( STAT3 ) in lipopolysaccharide (LPS) induced
IL-12p40 gene expression in bone marrow derived-dendritic cells ( BMDCs ) isolated from wild-type ( WT ) and IL-10 ( -/- ) mice
Ma et al., J Biol Chem 2009
(Acquired Immunodeficiency Syndrome) :
We have previously shown that lipopolysaccharide (LPS) induced
IL-12p40 production in monocytic cells is
regulated by
NFkappaB and AP-1 transcription factors through the activation of two distinct upstream signaling pathways, namely the c-Jun-N-terminal kinase (JNK) and the calmodulin dependent protein kinase-II activated pathways
Jan et al., Microbiol Immunol 2012
:
Inhibition of
nuclear factor (NF)-kappa B ( ?B ) by helenalin and p38 mitogen activated protein kinase ( MAPK ) by SB203580
prevented production of IL-12
p40 , IL-12 p70, and IL-10
Gri et al., J Biol Chem 1998
(Cell Transformation, Viral) :
While the NFkappaB and Ets sites appear equally critical for inducible p40 promoter activity in macrophage cell lines,
NFkappaB plays a more dominant role in the constitutive
p40 promoter activity in EBV+ B cells