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TLR2 — TLR3

Text-mined interactions from Literome

Harii et al., Mol Endocrinol 2005 (Thyroiditis, Autoimmune...) : We conclude that functional TLR3 are present on thyrocytes ; TLR3 downstream signals can be overexpressed by pathogen related stimuli ; overexpression can be reversed by phenylmethimazole to a significantly greater extent than MMI by inhibiting only the IFN regulatory factor-3/IFN-beta/signal transducers and activation of transcription arm of the TLR3 signal system ; and TLR3 overexpression can induce an innate immune response in thyrocytes, which may be important in the pathogenesis of Hashimoto 's thyroiditis and in the immune cell infiltrates
Flandin et al., Eur J Immunol 2006 (Inflammation...) : Furthermore, our data indicate a participation of TLR2 and TLR3 in the phagocytosis of L. donovani promastigotes and a role for TLR3 in the leishmanicidal activity of the IFN-gamma primed macrophages
Sel et al., J Immunol 2007 (Asthma...) : These data indicate that TLR-3 or TLR-7 activation by viral TLR ligands has both preventive as well as suppressive effects on experimental asthma which is mediated by the additive effects of IL-12 and IL-10
Wu et al., Int J Immunogenet 2008 : As an important member of TLRs, TLR1 is involved in the recognition of triacylated lipoproteins and mycobacterial products by binding to TLR2 to form a heterodimer
Aravalli et al., Journal of neuroinflammation 2008 (Histoplasmosis) : Furthermore, Yps3p induced TLR2 signaling was suppressed by vaccinia virus encoded TLR inhibitors
Regueiro et al., Infect Immun 2009 : We showed that Klebsiella induced TLR2 and TLR4 upregulation was dependent on TLR activation
So et al., Glia 2009 (Cardiovirus Infections) : Theiler 's virus infection induces TLR3 dependent upregulation of TLR2 critical for proinflammatory cytokine production ... More importantly, TLR3 was required for TMEV induced early TLR2 upregulation in primary astrocytes leading to the production of TLR2 dependent cytokines such as IL-6 ... These results indicate that TMEV utilizes TLR3 induced TLR2 to induce inflammatory cytokines, which are critical to the development of immune mediated demyelinating disease
Chamorro et al., J Immunol 2009 : TLR triggering on tolerogenic dendritic cells results in TLR2 up-regulation and a reduced proinflammatory immune program
Messlik et al., J Proteome Res 2009 (Chronic Disease...) : The aim of this study was to characterize the role of TLR2 or TLR4 deficiency in epithelial cell stress responses under noninflamed and inflamed conditions using TLR-deficient mice and TLR ( -/- ) cross bred IL-10-deficient mice as a model for genetically driven experimental colitis
Stridh et al., Journal of neuroinflammation 2011 (Hypoxia-Ischemia, Brain) : In contrast, TLR-2 was constitutively expressed in the brain and TLR-2 deficiency reduced HI injury
Kim et al., FEMS Microbiol Lett 2012 (Inflammation) : L. plantarum genomic DNA mediated inhibition of signaling pathway and tumor necrosis factor-alpha was accompanied by the suppression of toll-like receptor (TLR) 2 , TLR4, and TLR9 and the induction of interleukin-1 receptor associated kinase M, a negative regulator of TLR
Jia et al., Shanghai Kou Qiang Yi Xue 2011 : CD14, TLR4 receptors are involved in P.e-LPS effect and CD14, TLR2 and TLR4 receptors are involved in P.g-LPS effect in mouse osteoblast
Kumar et al., PloS one 2012 (Infection...) : Moreover, stimulation of the Muller glia with TLR 2 , 3, 4, 5, 7 and 9 agonists resulted in an increased TLR expression as assayed by Western blot and flow cytometry
Raicevic et al., Tissue Eng Part A 2012 : Inflammation was mimicked by a cytokine cocktail, and TLR activation was induced through TLR3 and TLR4 ligation
Melkamu et al., Journal of cell communication and signaling 2013 : These findings demonstrate that TLR3 activation differentially regulates TLR expression through autocrine signaling involving IL-6 secretion, IL-6Ra activation and subsequent phosphorylation of Stat3 ... The results also indicate that NF-?B and Stat3 are required for TLR3 dependent up-regulation of TLR2 and that its delayed expression was due to a requirement for IL-6 dependent Stat3 activation
Wang et al., PloS one 2012 (Cell Transformation, Neoplastic...) : TLR2 : TLR6 complexes mediate the effect of NF-?B inactivation by CDA-2
Feriotti et al., PloS one 2013 (Disease Susceptibility...) : Mannan or P. brasiliensis induced decreased expression of MR and TLR2 on A/J macrophages, whereas CR3, TLR4 and TLR2 were reduced on B10.A cells