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MT4 — TP53
Text-mined interactions from Literome
Fan et al., Br J Cancer 2002
(Breast Neoplasms) :
This study examines the
effect of tumour suppressor protein
p53 on
metallothionein expression following CdCl2 treatment in eight human epithelial breast cancer cell lines differing in p53 and oestrogen-receptor status ... This effect may be associated with the occurrence of apoptosis and suggests a
role for
p53 and oestrogen-receptor on the expression and induction of
metallothionein in epithelial cells
Liu et al., Toxicol Lett 2009
:
The present study was to investigate whether Ang II induces p53 expression and activation and if so, whether Ang II-induced cardiac cell death is p53 dependent, and whether a potent antioxidant
metallothionein ( MT ) prevents Ang II-induced
p53 expression, and associate apoptotic cell death signaling
Formigari et al., J Appl Toxicol 2013
(Hepatolenticular Degeneration) :
The protein
p53 also
plays a crucial role in the transcriptional regulation of
metallothionein , which indicates a novel regulatory role for p53