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ECM1 — IGF2
Text-mined interactions from Literome
Gooch et al., J Biol Chem 2001
(Hypertrophy) :
Therefore,
IGF-I induces hypertrophy and increases
ECM accumulation in MCs
Hsu et al., Am J Pathol 2008
(Pulmonary Fibrosis...) :
IGF-II triggered the activation of both phosphatidylinositol-3 kinase and Jun N-terminal kinase signaling cascades, the inhibition of which diminished
IGF-II induced
ECM production
Pricci et al., Endocrinology 1996
:
These experiments in cultured human mesangial cells were aimed at assessing the
effects of IGF-I and
IGF-II , compared with those of TGFbeta, on 1 )
ECM medium accumulation and gene expression, and 2 ) total protein synthesis and cell proliferation