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IGF1 — NOX5
Text-mined interactions from Literome
Tsukamoto et al., J Neurosci Res 2003
(Alzheimer Disease) :
Further investigation suggested that Abeta neurotoxicity via p75NTR involved JNK,
NADPH oxidase , and caspases-9/3 and was
inhibited by activity dependent neurotrophic factor,
insulin-like growth factor-I , basic fibroblast growth factor, and Humanin, as observed in primary neuron cultures
Edderkaoui et al., J Biol Chem 2011
(Pancreatic Neoplasms) :
Here we investigate the mechanisms through which
insulin-like growth factor I and serum ( FBS )
activate NADPH oxidase in pancreatic cancer ( PaCa ) cells ...
Insulin-like growth factor I and FBS
activate NADPH oxidase through transcriptional up-regulation of p22(phox)
New et al., Am J Physiol Cell Physiol 2012
:
Expression of dominant negative adenovirus Nox4 inhibits
IGF-I induced
NADPH oxidase activity, Akt phosphorylation, and fibronectin protein expression