Gene interactions and pathways from curated databases and text-mining

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ABL1 — RHOA

Text-mined interactions from Literome

Jones et al., J Neurosci 2004 : Biochemical assays using a glutathione S-transferase pull-down method to determine GTP bound active Rho GTPases demonstrate that Abl inhibition increases RhoA activity but has no effect on the activity of Rac1 or Cdc42
Sahay et al., Oncogene 2008 (Cell Transformation, Neoplastic...) : p210 Bcr-Abl can stimulate RhoA activation independently of its tyrosine kinase activity, and mutations within the RhoGEF domain that are predicted to eliminate RhoGEF activity inhibit RhoA activation