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Alpy et al., Oncogene 2003
(Breast Neoplasms) :
Since the ERBB2 promoter is also positively regulated by Sp1 , this study indicates that MLN64 and ERBB2 genes share common transcriptional controls together with a physical link on chromosome 17q
Spengler et al., Cell cycle (Georgetown, Tex.) 2008
:
PKC, ERK, and ERBB2 kinase inhibitors suppress PMA induction of Sp1 and the specific isozyme PKCalpha enhances Sp1 cleavage
Ye et al., Mol Cell Biol 1996
:
Sp1 binding plays a critical role in Erb-B2- and v-ras mediated downregulation of alpha2-integrin expression in human mammary epithelial cells