Gene interactions and pathways from curated databases and text-mining

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AVP — CA1

Text-mined interactions from Literome

Breyer et al., J Clin Invest 1991 : Because maneuvers that increase [ Ca++]i inhibit Na+ transport, the effects of AVP and cell-permeable cAMP analogues, on [ Ca++]i were investigated in fura-2 loaded in vitro microperfused rabbit CCDs. Low-dose AVP ( 23-230 pM ) selectively stimulated Ca++ influx, whereas 23 nM AVP additionally released calcium from intracellular stores. 8-chlorophenylthio-cAMP ( 8CPTcAMP ) and 8-bromo-cAMP ( 8-Br-cAMP ) also increased CCD [ Ca++]i
Jung et al., Biochem Biophys Res Commun 1991 : Moreover, pretreatment with both V1 and V2 antagonists in MTAL or OMCT completely inhibited the AVP induced [ Ca++]i transient, but in S1 partially blocked it
Quinn et al., Endocrinology 1990 : Cytosolic calcium (Cai) responses to arginine vasopressin (AVP) and angiotensin-II (Ang II) were examined in single rat adrenal zona glomerulosa ( ZG ) cells by monitoring fura-2 fluorescence with microspectrofluorimetry
Burnatowska-Hledin et al., Am J Physiol 1987 : The AVP induced increase in [ Ca]i from 61 +/- 6 to 225 +/- 44 nM ( n = 7, P less than 0.01 ) was rapid and transient, returning to base line in 2 to 3 min ... In MDCK cells, BK, but not AVP and PTH, increased [ Ca]i from 146 +/- 11 to 281 +/- 31 nM ( n = 9, P less than 0.001 )
Chen et al., J Pharmacol Exp Ther 1994 (Insulinoma) : At 8 microM, U-73122 abolished AVP 's effect on IP3 and [ Ca++]i , but AVP induced increases in insulin secretion were only reduced by 35 %
Gao et al., Endocrinology 1994 : In the presence of 15 mM glucose and 2.5 mM Ca2+, AVP and ACh stimulated inositol phosphate ( IP ) formation, increased cytoplasmic Ca2+ (Cai2+) , and potentiated insulin release ... Under these conditions, the effects of AVP and ACh on IP production and Cai2+ were practically abolished, and only ACh transiently increased insulin release
Chiodera et al., Eur J Clin Invest 1997 : These data demonstrate that AVP secretion is stimulated by a slight rapid increase in serum Cai levels even though absolute serum Cai levels remain within the normal range ... In addition, the positive correlation between Cai induced ACTH and AVP increments suggests that AVP plays a releasing role on ACTH secretion during calcium infusion
Touyz et al., J Pharmacol Exp Ther 1998 (Hypertension) : Basal and AVP stimulated [ Ca++]i responses were significantly increased ( p < .05 ) in SHR ( pD2 = 8.3 +/- 0.1, Emax = 532 +/- 14 nM for SHR ; pD2 = 8.0 +/- 0.04, Emax = 480 +/- 15 nM for WKY ) ... These findings demonstrate that Mg++ dose-dependently reduces [ Ca++]i and that high [ Mg++ ] e attenuates AVP stimulated [ Ca++]i responses and normalizes sensitivity to AVP in SHR