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IFNG — TNFSF4

Text-mined interactions from Literome

Grosenbach et al., Cell Immunol 2003 : These studies demonstrate that ( a) OX40L plays a role in sustaining the long-term proliferation of CD8 ( + ) T cells in addition to the known effect on CD4 ( + ) T cells following activation, ( b ) OX40L enhances the production of Th1 cytokines ( IL-2, IFN-gamma , and TNF-alpha ) from both CD4 ( + ) and CD8 ( + ) while no change in IL-4 expression was observed, and ( c ) the anti-apoptotic effect of OX40L on T cells is likely the result of sustained expression of anti-apoptotic genes while genes involved in apoptosis are inhibited
Zingoni et al., J Immunol 2004 : CD16 activated NK cells costimulate TCR induced proliferation, and IFN-gamma produced by autologous CD4+ T cells and this process is dependent upon expression of OX40 ligand and B7 by the activated NK cells
Liu et al., J Clin Invest 2008 (Melanoma, Experimental) : NK cell recruitment was mediated by CCR5 via chemokines secreted by pDCs, and optimal IFN-gamma production by NK cells was mediated by OX40L expressed by pDCs
Lee et al., Immunology 2008 : We found that de novo expression or overexpression of OX40L , 4-1BBL and IL-12p70 on activated B cells synergistically enhanced proliferation as well as IL-2 and interferon-gamma production by CD8+ T cells
Li et al., Cell Immunol 2008 : In agreement with prior reports, OX40L signaling through CD134 increased IFNgamma and IL-4, both of which are reported to inhibit the production of IL-17
Krimmer et al., Allergy 2009 (Asthma) : The aim of this study was to examine the effect of tumour necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on ASM CD40 and OX40L expression ... In contrast, IFN-gamma reduced TNF-alpha induced OX40L expression to a similar extent in both cell types ... IFN-gamma may regulate ASM pro-inflammatory actions by differentially modulating ASM CD40 and OX40L expression