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HMOX1 — NFE2

Text-mined interactions from Literome

Ali et al., J Biol Chem 2009 : Mechanistically, synergy required Akt phosphorylation, activation of Kruppel-like factor 2, NF-E2 related factor-2 (Nrf2), increased nitric-oxide synthase activity, and enhanced HO-1 mRNA stability
Takagi et al., Journal of clinical biochemistry and nutrition 2009 : Furthermore, NF-E2 related factor-2 (Nrf2) played an important role in HO-1 expression induced by lansoprazole
Takagi et al., J Pharmacol Exp Ther 2009 : In this study, we investigate the role of transcriptional NF-E2 related factor 2 (Nrf2) , its phosphorylation/activation, and oxidation of Kelch-like ECH associating protein 1 ( Keap1 ) in lansoprazole induced HO-1 up-regulation using cultured gastric epithelial cells ( rat gastric mucosal cell line, RGM-1 )
Kil et al., Journal of clinical biochemistry and nutrition 2012 : 3-Penten-2-one, of which structure, as in okanin, possesses the a-ß unsaturated carbonyl group, also induced nuclear factor-erythroid 2-related factor 2-dependent heme oxygenase-1 expression, while both 2-pentanone ( lacking a double bond ) and 2-pentene ( lacking a carbonyl group ) were virtually inactive
Soo Kim et al., J Ethnopharmacol 2012 : ASE significantly induced the expression and activity of heme oxygenase-1 (HO-1) , which is known to produce an anti-inflammatory effect, in RAW 264.7 cells, through NF-E2 related factor 2 (Nrf-2) , Janus kinase, and extracellular signal regulated kinase activation
Yoshino et al., Radiat Prot Dosimetry 2012 : In response to reactive oxygen species ( ROS ) or electrophiles, the transcription factor nuclear factor-erythroid 2 (NF-E2) related factor 2 ( Nrf2 ) rapidly translocates into the nucleus and induces the expression of various antioxidant genes, such as heme oxygenase-1 (HO-1)