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CBFA2T2 — NFKB1
Text-mined interactions from Literome
Sliva et al., J Biol Chem 2002
(Breast Neoplasms...) :
Although wortmannin, Ly294002, or overexpression of
p85DN did not significantly reduce DNA binding activity of NF-kappaB in nuclear extracts, wortmannin, Ly294002, and the overexpression of p85DN or IkappaBalpha
inhibited constitutive activation of
NF-kappaB in a reporter gene assay
Li et al., Infect Immun 2003
:
Moreover, a dominant negative mutant of
p85 ( p85-DN )
inhibited the
NF-kappa B luciferase activity, IL-6 production, and I kappa B alpha degradation elicited by LPS and IL-1 beta but not that stimulated by tumor necrosis factor alpha
Yan et al., Cancer Res 2010
(Carcinoma, Hepatocellular...) :
The interaction between RARgamma and
p85alpha resulted in activation of Akt and
NF-kappaB , critical regulators of the growth and survival of cancer cells