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CAV1 — CTSB
Text-mined interactions from Literome
Cavallo-Medved et al., J Cell Sci 2005
(Colonic Neoplasms) :
Caveolin-1 mediates the expression and localization of
cathepsin B , pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells ... In this study, we established a stable HCT 116 cell line with a gene encoding antisense caveolin-1 ( AS-cav-1 ) to examine the
effects of
caveolin-1 , the main structural protein of caveolae, on the expression and localization of
cathepsin B and pro-uPA, and their cell-surface receptors p11 and uPA receptor (uPAR), respectively ... Based on these results, we hypothesize that
caveolin-1 affects the expression and localization of
cathepsin B and pro-uPA, and their receptors, thereby mediating cell-surface proteolytic events associated with invasion of colon cancer cells
Yamaguchi et al., J Cell Physiol 2008
(Periodontitis) :
In this study, we investigated the
role of
Cav-1 on ( 1 ) the productivity, and ( 2 ) the enzymatic activity of
cathepsin B and L in human gingival fibroblasts ( HGFs ) treated with IL-6 in the presence of soluble form of IL-6 receptor ( sIL-6R )