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CADM1 — ERBB2

Text-mined interactions from Literome

Kawano et al., J Biol Chem 2009 : We found here that the ErbB3/ErbB2 signaling is regulated by immunoglobulin-like Necl-2 , which is down-regulated in various cancer cells and serves as a tumor suppressor
Mizutani et al., J Biol Chem 2011 : We previously showed that the immunoglobulin-like cell adhesion molecule Necl-2 ( Nectin-like molecule 2 ), known as a tumor suppressor, inhibits cancer cell movement by suppressing the ErbB3/ErbB2 signaling
Minami et al., J Biol Chem 2013 (Lung Neoplasms) : These results indicate that the suppressive role of Necl-2 in the HRG induced ErbB2/ErbB3 signaling is regulated by miR-199a at least through the reduction of the ST6GAL1 catalyzed sialylation of Necl-2 and/or through the reduction of the protein level of Necl-2 presumably by the protein degradation