Tanaka et al., J Immunol 2008
(Encephalomyelitis, Autoimmune, Experimental) :
IL-6 plus TGF-beta enhanced retinoic acid receptor related orphan receptor ( ROR ) -gammat expression and suppressed IFN-gamma production in wild-type T cells, whereas these effects were severely impaired in SOCS1-deficient T cells
Chen et al., Cell Biochem Biophys 2012
(Encephalomyelitis, Autoimmune, Experimental) :
We observed that overexpression of ROR?t in the presence of TGF-ß and IL-6 is highly efficient to produce Th17 cells